March 12, 2013 - 3:00pm
Experts at NYU Langone Medical Center presented new research and participated in expert panel discussions at the American College of Cardiology 62nd Annual Scientific Session held March 7-11, 2013 in San Francisco, California.
“This meeting provides an important opportunity for our leading scientists and cardiac experts to share in new discoveries in the treatment and prevention of cardiovascular disease,” said Glenn I. Fishman, MD
, the William Goldring Professor of Medicine, Department of Medicine and Director of the Leon H. Charney Division of Cardiology at NYU Langone. “We’re pleased to have the chance to contribute to the growing body of knowledge regarding cardiovascular health, as these advances will ultimately lead to enhanced patient care.”
Significant research findings from NYU Langone experts include:
Does Bariatric Surgery Ameliorate the Dyslipidemia of Obesity? Observations from Five Years of Followup After Gastric Banding
Amita Singh, MD
, Sean Heffron, MD, Jonathan Zagzag
, MD, Heekoung Youn, MD
, George Fielding, MD
, Christine Ren-Fielding, MD
, James Underberg, MD
Sunday, March 10 – 8:30am
This oral presentation focuses on the effects of bariatric surgery on lipoprotein particles. In obese patients, there is a typical "atherogenic" pattern of cholesterol abnormalities which includes elevated triglycerides, low high-density lipoprotein cholesterol (HDL, or "good" cholesterol) and seemingly normal low-density lipoprotein cholesterol (LDL, or "bad cholesterol"). However, the individual LDL particles (the carriers of cholesterol) can be small and numerous, which is a source of higher risk of cardiovascular disease. There is an abundance of evidence that bariatric surgery results in lower triglycerides and higher HDL, but little information on the effect on LDL particles and HDL particles, which are measured with a specific NMR blood test. The study results are consistent with prior studies where patients lost large amounts of weight, with improvements in triglycerides and increases in both HDL cholesterol and particle number, but surprisingly did not show any difference in LDL particle number or size.
10-Year Trends in Invasive Vs Conservative Management of Unstable Angina/Non-ST-Elevation Myocardial Infarction
Sunday, March 10 - 8:15am
The study assessed the ten year trend in invasive vs. conservative management of patients who present with non ST-segment elevation myocardial infarction or unstable angina using the Health Care Cost and Utilization Project dataset in over 4.5 million patients across the United States. Results found over the last decade there has been steady increase in the use of invasive strategy (cath) in patients with NSTEMI/UA; the proportion of patients who undergo invasive evaluation and who undergo percutaneous coronary intervention (PCI) has steadily increased while those undergoing coronary artery bypass grafting (CABG) has steadily decreased. The use of drug eluting stents increased to around a peak of 87 percent in 2005, then fell sharply and has made a partial recovery at around 67 percent. The in-hospital mortality has steadily decreased. We found overall, more needs to be done to improve these rates.